The biochemistry major provides interdisciplinary training, education and experience in the chemical and biological sciences. Biochemistry focuses on understanding the chemical processes of living organisms, the reaction pathways that sustain life, the principles of how structure defines function and the physical basis of biomolecular interactions. Students who major in biochemistry are prepared for diverse careers in medicine, scientific research, biotechnology, pharmacy, biomedical consulting, teaching and education, among other professions.
The undergraduate degree in biochemistry emphasizes knowledge and understanding of:
- Foundational principles of biology and chemistry.
- The building blocks of life (DNA, RNA and proteins), how they evolved, how they interact and how organisms make and degrade these building blocks.
- How living organisms maintain homeostasis and regulate metabolism.
- The molecular mechanisms of how living systems respond to changes, such as environmental perturbations, disease and chemical therapeutics.
- How chemical reactions impact human health.
The undergraduate degree in biochemistry also emphasizes and cultivates development of the following skills:
- Quantitative problem solving.
- Critical thinking and analytical reasoning.
- Communication of scientific concepts and ideas.
Because biochemistry connects to scientific disciplines ranging from genetics, human physiology, microbiology, neuroscience, cell biology, chemistry and geology, biochemistry majors are given the freedom to explore advanced electives in many of these subjects. Additional information about the biochemistry BA can be found on the Biochemistry Department website.
Biochemistry major students are prepared for many different careers after graduation. Career Services offers a number of programs and services designed to help students plan their career, including workshops, internships and placement services after graduation. For an appointment with a career counselor or for more information, call 303-492-6541 or stop by Center for Community, N352.
Undergraduate Research
Undergraduates are encouraged to participate in research to prepare themselves for graduate school, professional school or industry. There are multiple opportunities for undergraduates to be involved in research within the Department of Biochemistry. For more information, visit our Departmental Undergraduate research page.
Study Abroad
The experience of studying abroad can prove invaluable. For information about study abroad programs, visit the Education Abroad website.
Teaching Certification
Biochemistry majors can also earn certification as teachers through the School of Education. The program for a secondary school science-teaching certificate is challenging requiring a broad, strong background in science, as well as coursework in education and practice teaching. It usually requires at least five years of study. Students interested in teacher certification are encouraged to contact the School of Education.
Requirements
Program Requirements
The biochemistry major provides interdisciplinary training in the biological and chemical sciences, including courses in general chemistry, organic chemistry, physical chemistry and biochemistry, as well as in biology, calculus and physics.
Students must complete the general requirements of the College of Arts and Sciences and the required courses listed below. No more than 45 credits of CHEM and BCHM courses can be applied to the 120-credit minimum to graduate. All courses counted towards the major must be completed with a grade of C- or better and none of the courses may be taken for a pass/fail grade. The cumulative GPA in courses that can count toward the major must be at least 2.0.
Transfer students who plan to complete a BA degree in biochemistry must complete at the Boulder campus a minimum of 12 credits of upper-division courses in biochemistry covering at least two of the sub-disciplines in their major: organic, physical and biochemistry.
Students may want to consult each semester's Registration Handbook and Schedule of Courses, as well as the Professor Performance Guide for further information about course offerings and faculty.
Required Courses and Credits
Code | Title | Credit Hours |
---|---|---|
General Chemistry | ||
CHEM 1400 & CHEM 1401 | Foundations of Chemistry and Foundations of Chemistry Lab (Recommended) | 5 |
or CHEM 1113 & CHEM 1114 & CHEM 1133 & CHEM 1134 | General Chemistry 1 and Laboratory in General Chemistry 1 and General Chemistry 2 and Laboratory in General Chemistry 2 | |
Organic Chemistry | ||
CHEM 3451 | Organic Chemistry 1 for Chemistry and Biochemistry Majors (Recommended) | 4 |
or CHEM 3311 | Organic Chemistry 1 | |
CHEM 3321 | Laboratory in Organic Chemistry 1 | 1 |
BCHM 3491 | Organic Chemistry 2 for Biochemistry Majors (Recommended) | 4 |
or CHEM 3471 | Organic Chemistry 2 for Chemistry Majors | |
or CHEM 3331 | Organic Chemistry 2 | |
CHEM 3341 | Laboratory in Organic Chemistry 2 | 1-2 |
or CHEM 3381 | Laboratory in Advanced Organic Chemistry | |
Biochemistry | ||
BCHM 2700 | Foundations of Biochemistry | 4 |
BCHM 4720 | Metabolic Pathways and Human Disease | 4 |
BCHM 4740 | Biochemistry of Gene Transmission, Expression and Regulation 1 | 4 |
BCHM 4761 | Biochemistry Laboratory | 3 |
Physical Chemistry | ||
BCHM 4400 | Core Concepts in Physical Chemistry for Biochemists 2 | 4 |
Advanced Major Electives | ||
Select three of the following elective courses: | 9-12 | |
Engineering RNA Aptamers and Literature-based Co-seminar for BCHM 3100 CURE Laboratory Course | ||
Mechanisms of Cancer | ||
Principles of Pharmacology and Toxicology | ||
Modern Biophysical Methods | ||
Computational Genomics Lab | ||
Current Topics in Biochemical Research | ||
Therapeutic and Diagnostic Nucleic Acids | ||
Chemical Biology and Drug Design | ||
Matrix Methods and Applications | ||
Applied Probability | ||
Methods in Applied Mathematics: Complex Variables and Applications | ||
Biogeochemical Oceanography | ||
Modern Inorganic Chemistry | ||
Instrumental Analysis - Lecture and Laboratory 1 | ||
Instrumental Analysis - Lecture and Laboratory 2 | ||
Applied Data Analysis | ||
Chemical Engineering Fluid Mechanics | ||
Chemical Engineering Heat and Mass Transfer | ||
Principles of Genetics (cannot also count EBIO 2070 as a required ancillary course or an advanced elective) | ||
Synthetic Biology: Engineering Biomolecular Systems in the Laboratory | ||
Cell Biology | ||
Biology of the Cancer Cell | ||
Infectious Disease | ||
Fertility, Sterility, and Early Mammalian Development | ||
Biological Data Science | ||
Structural Methods for Biological Macromolecules | ||
The Brain - From Molecules to Behavior | ||
Introduction to Systems Biololgy for Biologists | ||
Immunology (cannot also count IPHY 4600 as a required Advanced Major Elective) | ||
Microbial Genetics and Physiology | ||
Microbial Diversity and the Biosphere | ||
Human Molecular Genetics | ||
Cell Signaling and Developmental Regulation | ||
Cellular Basis of Disease | ||
Mechanisms of Gene Regulation in Eukaryotes | ||
Bioinformatics and Genomics | ||
Biology of Stem Cells | ||
Animal Virology | ||
Oocytes, Stem Cells, Organisms: Experiments to Discoveries | ||
Genetics: Molecules to Populations (cannot also count MCDB 2150 as a required ancillary course or an advanced elective) | ||
Conservation Biology | ||
Evolutionary Biology | ||
Global Ecology | ||
Tropical Marine Ecology | ||
Animal Behavior | ||
Microbiology | ||
The Art and Strategy of Science Communication: Branding Climate Change | ||
Plants and Society | ||
Parasitology | ||
Animal Diversity: Invertebrates | ||
Limnology | ||
Landscape Ecology | ||
Freshwater Phycology | ||
Plant Ecology | ||
Ecosystem Ecology | ||
Phylogenetics and Comparative Biology | ||
Biological Statistics | ||
Computational Biology | ||
Animal Developmental Diversity | ||
Plant Biodiversity and Evolution | ||
Plant Anatomy and Development | ||
Critical Thinking in Biology | ||
Human Anatomy | ||
Human Physiology | ||
Introduction to Epidemiology | ||
Endocrinology | ||
Biology of Human Reproduction | ||
Immunology (cannot also count MCDB 4300 as a required Advanced Major Elective) | ||
Neurophysiology | ||
Introduction to Mathematical Statistics | ||
The Python Project | ||
Developmental Biology | ||
Molecular Neurobiology | ||
Introduction to Neuroscience | ||
Neurobiology of Learning and Memory | ||
Neural Circuits of Learning and Decision Making | ||
Behavioral Neuroendocrinology | ||
Neuropharmacology | ||
Neurobiology of Addiction | ||
Behavioral Genetics | ||
Introduction to Geochemistry | ||
Introduction to Biogeochemistry | ||
Marine Chemistry and Geochemistry | ||
Cosmochemistry | ||
Isotope Geology | ||
Stable Isotopes in Paleoclimate and Paleoecology | ||
Environmental Ethics (cannot also count PHIL 3160 as a required Advanced Major Elective) | ||
Bioethics (cannot also count PHIL 3140 as a required Advanced Major Elective) | ||
Total Credit Hours | 43-47 |
Required Ancillary Coursework from Outside Biochemistry
Code | Title | Credit Hours |
---|---|---|
Physics | ||
PHYS 1110 | General Physics 1 | 4 |
PHYS 1120 | General Physics 2 | 4 |
PHYS 1140 | Experimental Physics 1 | 1 |
Calculus | ||
MATH 1300 | Calculus 1 | 4-5 |
or MATH 1310 | Calculus for Life Sciences | |
or APPM 1350 | Calculus 1 for Engineers | |
MATH 2300 | Calculus 2 | 4-5 |
or APPM 1360 | Calculus 2 for Engineers | |
Biology Sequence with Labs | ||
Lectures (One of the following sequences) | 6 | |
Introduction to Cellular and Molecular Biology and Principles of Genetics | ||
MCDB 1111 & MCDB 2222 | and | |
General Biology 1 and General Biology 2 | ||
Labs (One of the following sequences) | 2 | |
From Dirt to DNA: Phage Genomics Laboratory I | ||
or MCDB 1171 | Antibiotics Discovery Through Hands-on Screens I | |
or MCDB 2171 | Chemotherapeutic Discovery Through Hands-On Screens 2 | |
General Biology Laboratory 1 and General Biology Laboratory 2 | ||
Total Credit Hours | 25-27 |
1 | BCHM 4740 can be waived upon completion of the MCDB major. |
2 |
All students, and especially those intending to go onto graduate school in biochemistry, will benefit from additional advanced courses. Recommended electives include graduate courses in various fields of chemistry, or advanced courses in biology or mathematics.
Graduating in Four Years
Consult the Four-Year Guarantee Requirements for information on eligibility. The concept of "adequate progress" as it is used here only refers to maintaining eligibility for the four-year guarantee; it is not a requirement for the major. To maintain progress in biochemistry, students should declare the biochemistry major in the first semester.
Students must consult with a major advisor to determine adequate progress toward completion of the major.
Recommended Four-Year Plan of Study
Through the required coursework for the major, students will fulfill all 12 credits of the Natural Sciences area of the Gen Ed Distribution Requirement, including the required laboratory or field experience, and the QRMS component of the Gen Ed Skills Requirement.
Year One | ||
---|---|---|
Fall Semester | Credit Hours | |
CHEM 1400 | Foundations of Chemistry | 4 |
CHEM 1401 | Foundations of Chemistry Lab | 1 |
MATH 1300 | Calculus 1 or Calculus for Life Sciences or Calculus 1 for Engineers | 4-5 |
Gen. Ed. Distribution course (example: Social Sciences) | 3 | |
Gen. Ed. Skills course (example: Lower-division Written Communication) | 3 | |
Credit Hours | 15-16 | |
Spring Semester | ||
CHEM 3451 | Organic Chemistry 1 for Chemistry and Biochemistry Majors | 4 |
CHEM 3321 | Laboratory in Organic Chemistry 1 | 1 |
MATH 2300 or APPM 1360 | Calculus 2 or Calculus 2 for Engineers | 4-5 |
Gen. Ed. Distribution/Diversity course (example: Arts & Humanities/US Perspective) | 3 | |
Gen. Ed. Distribution/Diversity course (example: Social Sciences/Global Perspective) | 3 | |
Credit Hours | 15-16 | |
Year Two | ||
Fall Semester | ||
BCHM 3491 | Organic Chemistry 2 for Biochemistry Majors | 4 |
CHEM 3341 | Laboratory in Organic Chemistry 2 | 1 |
MCDB 1150 or MCDB 1111 or EBIO 1210 | Introduction to Cellular and Molecular Biology or or General Biology 1 | 3 |
MCDB 1161 | From Dirt to DNA: Phage Genomics Laboratory I or Antibiotics Discovery Through Hands-on Screens I or General Biology Laboratory 1 | 2 |
Gen. Ed. Distribution course (example: Social Sciences) | 3 | |
Gen. Ed. Distribution course (example: Arts & Humanities) | 3 | |
Credit Hours | 16 | |
Spring Semester | ||
BCHM 2700 | Foundations of Biochemistry | 4 |
MCDB 2150 or MCDB 2222 or EBIO 1220 | Principles of Genetics or or General Biology 2 | 3 |
MCDB 1171 | Antibiotics Discovery Through Hands-on Screens I or Chemotherapeutic Discovery Through Hands-On Screens 2 or General Biology Laboratory 2 | 2 |
Gen. Ed. Distribution course (example: Social Sciences) | 3 | |
Elective | 3 | |
Credit Hours | 15 | |
Year Three | ||
Fall Semester | ||
BCHM 4720 | Metabolic Pathways and Human Disease | 4 |
PHYS 1110 | General Physics 1 | 4 |
Gen. Ed. Distribution course (example: Social Sciences) | 3 | |
Elective | 3 | |
Credit Hours | 14 | |
Spring Semester | ||
BCHM 4740 | Biochemistry of Gene Transmission, Expression and Regulation | 4 |
PHYS 1120 | General Physics 2 | 4 |
PHYS 1140 | Experimental Physics 1 | 1 |
Gen. Ed. Skills course (example: Upper-division Written Communication) | 3 | |
Elective | 3 | |
Credit Hours | 15 | |
Year Four | ||
Fall Semester | ||
BCHM 4400 | Core Concepts in Physical Chemistry for Biochemists | 4 |
Advanced Major Elective | 3 | |
Advanced Major Elective | 3 | |
Gen. Ed. Distribution (example: Arts & Humanities) | 3 | |
Elective | 3 | |
Credit Hours | 16 | |
Spring Semester | ||
BCHM 4761 | Biochemistry Laboratory | 3 |
Advanced Major Elective | 3 | |
Gen. Ed. Distribution course (example: Arts & Humanities) | 3 | |
Elective | 3 | |
Elective | 3 | |
Credit Hours | 15 | |
Total Credit Hours | 121-123 |
Learning Outcomes
Upon completing the program, students will be able to:
- Master the foundational concepts of general and organic chemistry, including equilibrium, kinetics, bonding (covalent and non-covalent) and reactivity and apply these concepts to biological systems.
- Explain how biomolecules (DNA, RNA, proteins, lipids, carbohydrates and metabolites) are synthesized and control biological processes.
- Identify the factors that determine the three-dimensional structures of biological macromolecules (DNA, RNA, proteins), and membranes (including organelles) and explain how structure relates to function.
- Describe how cells sense their environment and use this information to regulate cellular functions such as DNA replication, gene expression, signal transduction, cell division and cell death.
- Develop a conceptual, mechanistic and mathematical understanding of biomolecular interactions, including binding and catalysis.
- Explain how energy is stored, transformed and harnessed in biological systems.
- Analyze data, interpret graphs, solve quantitative problems to interpret results of scientific studies. Evaluate the rigor and reproducibility of scientific results.
- Learn and apply the rigorous scientific methods on which (bio)chemical knowledge is built: making observations, formulating hypotheses, executing experiments, evaluating rigor and reproducibility.
- Effectively communicate scientific information in oral, written and visual formats to specialized and general audiences.