The biochemistry major provides interdisciplinary training, education and experience in the chemical and biological sciences. Biochemistry focuses on understanding the chemical processes of living organisms, the reaction pathways that sustain life, the principles of how structure defines function and the physical basis of biomolecular interactions. Students who major in biochemistry are prepared for diverse careers in medicine, scientific research, biotechnology, pharmacy, biomedical consulting, teaching and education, among other professions.

 The undergraduate degree in biochemistry emphasizes knowledge and understanding of:

  • Foundational principles of biology and chemistry.
  • The building blocks of life (DNA, RNA and proteins), how they evolved, how they interact and how organisms make and degrade these building blocks.
  • How living organisms maintain homeostasis and regulate metabolism.
  • The molecular mechanisms of how living systems respond to changes, such as environmental perturbations, disease and chemical therapeutics.
  • How chemical reactions impact human health.

The undergraduate degree in biochemistry also emphasizes and cultivates development of the following skills:

  • Quantitative problem solving.
  • Critical thinking and analytical reasoning.
  • Communication of scientific concepts and ideas.

Because biochemistry connects to scientific disciplines ranging from genetics, human physiology, microbiology, neuroscience, cell biology, chemistry and geology, biochemistry majors are given the freedom to explore advanced electives in many of these subjects. Additional information about the biochemistry BS can be found on the Biochemistry Department website.

Biochemistry major students are prepared for many different careers after graduation. Career Services offers a number of programs and services designed to help students plan their career, including workshops, internships and placement services after graduation. For an appointment with a career counselor or for more information, call 303-492-6541 or stop by Center for Community, N352.

Undergraduate Research

Undergraduates are encouraged to participate in research to prepare themselves for graduate school, professional school or industry. There are multiple opportunities for undergraduates to be involved in research within the Department of Biochemistry. For more information, visit our Departmental Undergraduate research page.

Study Abroad

The experience of studying abroad can prove invaluable. For information about study abroad programs, visit the Education Abroad website.

Teaching Certification

Biochemistry majors can also earn certification as teachers through the School of Education. The program for a secondary school science-teaching certificate is challenging requiring a broad, strong background in science, as well as coursework in education and practice teaching. It usually requires at least five years of study. Students interested in teacher certification are encouraged to contact the School of Education.

Requirements 

Program Requirements

The biochemistry major provides interdisciplinary training in the biological and chemical sciences, including courses in general chemistry, organic chemistry, physical chemistry and biochemistry, as well as in biology, calculus and physics.

Students must complete the general requirements of the College of Arts and Sciences and the required courses listed below. No more than 66 credits of CHEM and BCHM courses can be applied to the 120-credit minimum to graduate. All courses counted towards the major must be completed with a grade of C- or better and none of the courses may be taken for a pass/fail grade. The cumulative GPA in courses that can count toward the major must be at least 2.000.

Transfer students who plan to complete a BS degree in biochemistry must complete at the Boulder campus a minimum of 12 credits of upper-division courses in biochemistry.

Students may want to consult each semester's Registration Handbook and Schedule of Courses, as well as the Professor Performance Guide for further information about course offerings and faculty.

Required Courses and Credits

General Chemistry
CHEM 1400
CHEM 1401
Foundations of Chemistry
and Foundations of Chemistry Lab (Recommended)
5
or CHEM 1113
CHEM 1114
CHEM 1133
CHEM 1134
General Chemistry 1
and Laboratory in General Chemistry 1
and General Chemistry 2
and Laboratory in General Chemistry 2
Organic Chemistry
CHEM 3451Organic Chemistry 1 for Chemistry and Biochemistry Majors (Recommended)4
or CHEM 3311 Organic Chemistry 1
CHEM 3321Laboratory in Organic Chemistry 11
BCHM 3491Organic Chemistry 2 for Biochemistry Majors (Recommended)4
or CHEM 3471 Organic Chemistry 2 for Chemistry Majors
or CHEM 3331 Organic Chemistry 2
CHEM 3341Laboratory in Organic Chemistry 21-2
or CHEM 3381 Laboratory in Advanced Organic Chemistry
Biochemistry
BCHM 2700Foundations of Biochemistry4
BCHM 4720Metabolic Pathways and Human Disease4
BCHM 4740Biochemistry of Gene Transmission, Expression and Regulation 14
BCHM 4761Biochemistry Laboratory3
Physical Chemistry
BCHM 4400Core Concepts in Physical Chemistry for Biochemists 24
Advanced Major Electives
Select three of the following elective courses:9-12
BCHM 3100
BCHM 3110
Engineering RNA Aptamers
and Literature-based Co-seminar for BCHM 3100 CURE Laboratory Course
3
BCHM 3300Genetic Engineering: Science, Technology, and Society3
BCHM 3341Chemical Biology and Molecular Therapeutics3
BCHM 3400Mechanisms of Cancer (cannot also count MCDB 3150 as a required Advanced Major Elective)3
BCHM 3450Principles of Pharmacology and Toxicology3
BCHM 4312Quantitative Optical Imaging3
BCHM 4491Modern Biophysical Methods3
BCHM 4631Computational Genomics Lab (cannot also count MCDB 3450 as a required Advanced Major Elective)3
BCHM 4751Current Topics in Biochemical Research3
BCHM 4850Therapeutic and Diagnostic Nucleic Acids3
APPM 3310Matrix Methods and Applications3
APPM 3570Applied Probability3
ATOC 4200Biogeochemical Oceanography3
CHEM 4011Modern Inorganic Chemistry3
CHEM 4171Instrumental Analysis - Lecture and Laboratory 13
CHEM 4181Instrumental Analysis - Lecture and Laboratory 23
CHEN 3010Applied Data Analysis3
EBIO 2070Genetics: Molecules to Populations (cannot also count MCDB 2150 as a required ancillary course or an advanced elective)4
EBIO 3040Conservation Biology4
EBIO 3080Evolutionary Biology4
EBIO 3180Global Ecology3
EBIO 3190Tropical Marine Ecology3
EBIO 3240Animal Behavior4
EBIO 3400Microbiology3
EBIO 3523The Art and Strategy of Science Communication: Branding Climate Change3
EBIO 3590Plants and Society4
EBIO 3630Parasitology4
EBIO 3850Animal Diversity: Invertebrates4
EBIO 4030Limnology3
EBIO 4060Landscape Ecology3
EBIO 4080Freshwater Phycology4
EBIO 4140Plant Ecology3
EBIO 4155Ecosystem Ecology4
EBIO 4290Phylogenetics and Comparative Biology4
EBIO 4410Biological Statistics (cannot also count CHEN 3010, IPHY 3280, or MATH 2510 as a required Advanced Major Elective)4
EBIO 4420Computational Biology3
EBIO 4440Animal Developmental Diversity4
EBIO 4500Plant Biodiversity and Evolution4
EBIO 4510Plant Anatomy and Development4
EBIO 4800Critical Thinking in Biology3
ENVS 4185Geomicrobiology3
ERTH 3181Microbial Planet Laboratory4
ERTH 3320Introduction to Geochemistry3
ERTH 4185Geomicrobiology3
ERTH 4270Marine Chemistry and Geochemistry3
ERTH 4330Cosmochemistry3
ERTH 4670Isotope Geology3
IPHY 3280Intro to Data Science and Biostatistics (cannot also count CHEN 3010, EBIO 4410 or MATH 2510 as a required Advanced Major Elective)4
IPHY 3410Human Anatomy3
IPHY 3430Human Physiology4
IPHY 3490Introduction to Epidemiology3
IPHY 4440Endocrinology4
IPHY 4470Biology of Human Reproduction3
IPHY 4600Immunology (cannot also count MCDB 4300 as a required Advanced Major Elective)3
IPHY 4720Neurophysiology4
MATH 2510Introduction to Statistics (cannot also count CHEN 3010, EBIO 4410 or IPHY 3280 as a required Advanced Major Elective)3
MATH 4520Introduction to Mathematical Statistics3
MCDB 2150Principles of Genetics (cannot also count EBIO 2070 as a required ancillary course or an advanced elective)3
MCDB 3145Cell Biology3
MCDB 3150Biology of the Cancer Cell (cannot also count BCHM 3400 as a required Advanced Major Elective)3
MCDB 3160Infectious Disease3
MCDB 3181Microbial Planet Laboratory4
MCDB 3350Fertility, Sterility, and Early Mammalian Development3
MCDB 3450Biological Data Science (cannot also count BCHM 4631 as a required Advanced Major Elective)3
MCDB 3501Structural Methods for Biological Macromolecules3
MCDB 3650The Brain - From Molecules to Behavior3
MCDB 3990Introduction to Systems Biololgy for Biologists3
MCDB 4185Geomicrobiology3
MCDB 4202The Python Project3
MCDB 4300Immunology (cannot also count IPHY 4600 as a required Advanced Major Elective)4
MCDB 4310Microbial Genetics and Physiology3
MCDB 4312Quantitative Optical Imaging3
MCDB 4350Microbial Diversity and the Biosphere3
MCDB 4410Human Molecular Genetics3
MCDB 4426Cell Signaling and Developmental Regulation3
MCDB 4444Cellular Basis of Disease3
MCDB 4471Mechanisms of Gene Regulation in Eukaryotes3
MCDB 4520Bioinformatics and Genomics3
MCDB 4615Biology of Stem Cells3
MCDB 4650Developmental Biology3
MCDB 4750Animal Virology3
MCDB 4777Molecular Neurobiology3
MCDB 4790Oocytes, Stem Cells, Organisms: Experiments to Discoveries3
NRSC 2125Introduction to Neuroscience I: Foundations4
NRSC 4032Neurobiology of Learning and Memory3
NRSC 4082Neural Circuits of Learning and Decision Making3
NRSC 4092Behavioral Neuroendocrinology3
NRSC 4132Neuropharmacology3
NRSC 4545Neurobiology of Addiction3
PHIL 3140Environmental Ethics (cannot also count PHIL 3160 as a required Advanced Major Elective)3
PHIL 3160Bioethics (cannot also count PHIL 3140 as a required Advanced Major Elective)3
PSYC 3102Behavioral Genetics3
Total Credit Hours43-47

Required Ancillary Coursework from Outside Biochemistry

Physics
PHYS 1110General Physics 14
PHYS 1120General Physics 24
PHYS 1140Experimental Physics 11
Calculus
MATH 1300Calculus 14-5
or MATH 1310 Calculus for Life Sciences
or APPM 1350 Calculus 1 for Engineers
MATH 2300Calculus 24-5
or APPM 1360 Calculus 2 for Engineers
Biology Sequence with Labs
Lectures (One of the following sequences)6
MCDB 1150
MCDB 2150
Introduction to Cellular and Molecular Biology
and Principles of Genetics
6
EBIO 1210
EBIO 1220
General Biology 1
and General Biology 2
6
Labs (One of the following sequences)2
MCDB 1161From Dirt to DNA: Phage Genomics Laboratory I2
or MCDB 1171 Antibiotics Discovery Through Hands-on Screens I
or MCDB 2171 Chemotherapeutic Discovery Through Hands-On Screens
EBIO 1230
EBIO 1240
General Biology Laboratory 1
and General Biology Laboratory 2
2
Total Credit Hours25-27

All students, and especially those intending to go onto graduate school in biochemistry, will benefit from additional advanced courses. Recommended electives include graduate courses in various fields of chemistry, or advanced courses in biology or mathematics.

Graduating in Four Years

Consult the Four-Year Guarantee Requirements for information on eligibility. The concept of "adequate progress" as it is used here only refers to maintaining eligibility for the four-year guarantee; it is not a requirement for the major. To maintain progress in biochemistry, students should declare the biochemistry major in the first semester.

Students must consult with a major advisor to determine adequate progress toward completion of the major.

Recommended Four-Year Plan of Study

Through the required coursework for the major, students will fulfill all 12 credits of the Natural Sciences area of the Gen Ed Distribution Requirement, including the required laboratory or field experience, and the QRMS component of the Gen Ed Skills Requirement.

Plan of Study Grid
Year One
Fall SemesterCredit Hours
CHEM 1400 Foundations of Chemistry 4
CHEM 1401 Foundations of Chemistry Lab 1
BCHM 1020 A Path to Success: Introduction to the Biochemistry Major 1
MATH 1300
Calculus 1
or Calculus for Life Sciences
or Calculus 1 for Engineers
4-5
Gen. Ed. Skills course (example: Lower-division Written Communication) 3
 Credit Hours13-14
Spring Semester
CHEM 3451 Organic Chemistry 1 for Chemistry and Biochemistry Majors 4
CHEM 3321 Laboratory in Organic Chemistry 1 1
MATH 2300
Calculus 2
or Calculus 2 for Engineers
4-5
Gen. Ed. Distribution & Diversity course (example: Arts & Humanities/US Perspective) 3
Gen. Ed. Distribution & Diversity course (example: Social Sciences/Global Perspective) 3
 Credit Hours15-16
Year Two
Fall Semester
BCHM 3491 Organic Chemistry 2 for Biochemistry Majors 4
CHEM 3341 Laboratory in Organic Chemistry 2 1
MCDB 1150
Introduction to Cellular and Molecular Biology
or General Biology 1
3
MCDB 1161
From Dirt to DNA: Phage Genomics Laboratory I
or Antibiotics Discovery Through Hands-on Screens I
or General Biology Laboratory 1
2-1
Gen. Ed. Distribution course (example: Social Sciences) 3
Gen. Ed. Distribution course (example: Arts & Humanities) 3
 Credit Hours16-15
Spring Semester
BCHM 2700 Foundations of Biochemistry 4
MCDB 2150
Principles of Genetics
or General Biology 2
3
EBIO 1240 General Biology Laboratory 2 (Only needed if took EBIO 1230 in Fall) 0-1
Gen. Ed. Distribution course (example: Social Sciences) 3
Gen. Ed. Distribution course (example: Social Sciences) 3
Elective 3
 Credit Hours16-17
Year Three
Fall Semester
BCHM 4720 Metabolic Pathways and Human Disease 4
PHYS 1110 General Physics 1 4
Gen. Ed. Distribution course (example: Arts & Humanities) 3
Elective 3
 Credit Hours14
Spring Semester
BCHM 4740 Biochemistry of Gene Transmission, Expression and Regulation 4
PHYS 1120 General Physics 2 4
PHYS 1140 Experimental Physics 1 1
Gen. Ed. Skills course (example: Upper-division Written Communication) 3
Elective 3
 Credit Hours15
Year Four
Fall Semester
BCHM 4400 Core Concepts in Physical Chemistry for Biochemists 4
BCHM Advanced Major Elective 3
BCHM Advanced Major Elective 3
Gen. Ed. Distribution (example: Arts & Humanities) 3
Elective 3
 Credit Hours16
Spring Semester
BCHM 4761 Biochemistry Laboratory 3
BCHM Advanced Major Elective 3
Gen. Ed. Distribution course (example: Arts & Humanities) 3
Elective (May need to be Upper Division depending on course choices) 3
Elective 3
 Credit Hours15
 Total Credit Hours120-122

Learning Outcomes

By the completion of the program, students will be able to:

  • Master the foundational concepts of general and organic chemistry, including equilibrium, kinetics, bonding (covalent and non-covalent) and reactivity and apply these concepts to biological systems.
  • Explain how biomolecules (DNA, RNA, proteins, lipids, carbohydrates and metabolites) are synthesized and control biological processes.
  • Identify the factors that determine the three-dimensional structures of biological macromolecules (DNA, RNA, proteins), and membranes (including organelles) and explain how structure relates to function.
  • Describe how cells sense their environment and use this information to regulate cellular functions such as DNA replication, gene expression, signal transduction, cell division and cell death.
  • Develop a conceptual, mechanistic and mathematical understanding of biomolecular interactions, including binding and catalysis.
  • Explain how energy is stored, transformed and harnessed in biological systems.
  • Analyze data, interpret graphs, solve quantitative problems to interpret results of scientific studies. Evaluate the rigor and reproducibility of scientific results.
  • Learn and apply the rigorous scientific methods on which (bio)chemical knowledge is built: making observations, formulating hypotheses, executing experiments, evaluating rigor and reproducibility.
  • Effectively communicate scientific information in oral, written and visual formats to specialized and general audiences.